KMID : 0614620120590040303
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Korean Journal of Gastroenterology 2012 Volume.59 No. 4 p.303 ~ p.307
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A Case of Cytomegalovirus Colitis with Endoscopic Finding Resembling Crohn¡¯s Disease
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Huh Cheal-Wung
Yoon Young-Hoon Jung Da-Hyun Kim Do-Whan Kho Bo-Gun Kim Jie-Hyun Park Hyo-Jin Lee Sang-In
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Abstract
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Cytomegalovirus (CMV) colitis is common among immunocompromised patients, and often diagnosed by pathologic confirmation because it is associated with a diverse spectrum of clinical and endoscopic features. However, Crohn¡¯s disease has no definitive diagnostic criteria, but longitudinal ulcers and cobble stone appearance are accepted as typical endoscopic features of Crohn¡¯s disease. An 83 year-old male with a history of radiotherapy for hypopharyngeal cancer visited our hospital with a complaint of melena for 1 week. His colonoscopic exam showed multiple longitudinal ulcers along the entire colon. Most of the ulcers were longer than 4 cm, these endoscopic findings were suspected as typical endoscopic features of Crohn¡¯s disease. Pathologic reports revealed multiple inclusion bodies with CMV on immunohistochemistry. He was finally diagnosed as having CMV colitis, and received a 3 week-course of intravenous ganciclovir. A colonoscopic follow-up showed complete healing of the multiple longitudinal ulcers, and he is doing well now without further treatment.
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KEYWORD
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Cytomegalovirus colitis, Longitudinal ulcer, Crohn¡¯s disease
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